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The original GAinS study, which has now closed, recruited a total of 2404 patients with community acquired pneumonia or faecal peritonitis, making this one of the largest bio-repositories of sepsis cases in the world.

Funded by an MRC Research Grant of more than £900,000 GAinS2/sepsis immunomics has started to recruit all cause sepsis patients to a multi-omic study of the host response to sepsis, which includes ward based cases and convalescent samples, as well as patients admitted to intensive care. The overall objective of this study is to further our understanding of the host/immune response in sepsis to inform a precision medicine approach to management. Although currently recruitment is confined to Oxford we plan to expand to include additional sites in the coming months.